About

Staff-level full-stack engineer with 9+ years of experience leading high-impact healthcare and data products from ambiguous problem to reliable production system. Combines hands-on expertise in React, Python, cloud infrastructure, and data platforms with a record of setting technical direction, modernizing legacy systems, and multiplying team effectiveness. Builds human-centered software, applies AI thoughtfully across engineering workflows, and turns complex operational needs into measurable business and clinical outcomes.

Website crystalprism.io
Location Philadelphia, PA
LinkedIn esther-hoffman
GitHub estherh5

Skills

Engineering

  • React
  • TypeScript
  • JavaScript
  • Vue
  • Python
  • Flask
  • PostgreSQL
  • HTML
  • CSS / Sass

Platform & Data

  • AWS
  • Google Cloud
  • Docker
  • Kubernetes
  • SQL / Firestore
  • Analytics / Looker
  • CI/CD
  • Performance
  • Authentication

Leadership & AI

  • System architecture
  • Technical leadership
  • Code review & mentorship
  • Technical strategy
  • AI-assisted development
  • Prompt engineering
  • AI evaluation & guardrails
  • Workflow automation
  • Human-centered design

Experience

Invitae, now part of Labcorp

Senior Software Engineer
- Present
invitae.com

Technical lead for laboratory data, analysis, and operations software supporting genetic testing workflows.

  • Owns technical direction and delivery for multiple laboratory applications built with React, Python/Flask, PostgreSQL, Docker, and AWS, leading initiatives from discovery through production operations.
  • Serves as Frontend Lead, establishing architecture, engineering standards, reusable patterns, and review practices that improve consistency and maintainability across teams.
  • Modernized legacy systems with shared APIs and reusable components, reducing complexity while making critical workflows easier to extend and support.
  • Improved an internal dashboard's performance by 20x, returning an estimated eight hours per day to clinical teams.
  • Introduced caching and a metrics dashboard that eliminated an estimated 16 hours of daily manual work for client services.
  • Architected and delivered a DNA sequencing plate viewer and a secure data-management application, translating specialized laboratory needs into intuitive tools for quality analysis and operations.
  • Uses AI-assisted engineering workflows for technical discovery, implementation, testing, refactoring, and documentation, with deliberate human review and quality safeguards.

Bainbridge Health

Senior Software Engineer
-
bainbridgehealth.com

Full-stack technical leader for a medication safety analytics platform used by healthcare organizations.

  • Led architecture and development across a Vue, Python/Flask, Looker, Firestore, Kubernetes, and Google Cloud platform.
  • Initiated a cross-service performance program and reduced application load times by 10x.
  • Designed and delivered real-time job monitoring and operational controls backed by the Kubernetes API, improving visibility into critical data ingestion workflows.
  • Partnered with engineering and customer success to set product priorities, shape monthly goals, and raise quality through code review and technical guidance.

Software Engineer
-

Full-stack engineer building secure, data-intensive healthcare products and platform foundations.

  • Built a medication analytics platform with Vue, Python/Flask, MySQL, Docker, Kubernetes, and Google Cloud, converting complex clinical data into actionable safety recommendations.
  • Implemented enterprise single sign-on and multi-factor authentication with Google Identity Platform and ADFS.
  • Architected and executed a MySQL-to-Firestore migration that reduced monthly query costs by thousands of dollars.
  • Established product analytics foundations and business intelligence visualizations for user behavior, KPIs, and performance metrics.
  • Built a 180-scenario behavior-driven integration test suite with Selenium and pytest, improving confidence in platform releases.

NoBugs! Pest Control Supplies

Web Developer & Project Manager
-

Independent developer and project manager modernizing a local business's digital and operational systems.

  • Designed, built, secured, and operated the company's responsive web presence with JavaScript, Python/Flask, Netlify, and Google Cloud.
  • Automated inventory and customer communications, saving the business more than $1,000 per month.
  • Managed a complex property renovation, coordinating architects, schedules, requirements, and design approvals.

Epic

Software Project Manager, Team Lead & Application Success Owner
-
epic.com

Technical program leader for enterprise electronic health record implementations at four healthcare systems.

  • Led multi-year software implementations spanning configuration, demonstrations, project planning, timelines, budgets, testing, training, and go-live readiness.
  • Managed and mentored a team of project managers, setting expectations, coaching performance, and recovering at-risk programs.
  • Owned two core third-party integrations end to end, aligning clinicians and engineers on requirements, constraints, testing, rollout, and support.
  • Redesigned the development intake process with engineering leadership, applying Agile practices to deliver more than 30 customer-requested features.
  • Earned Lean Six Sigma and Epic certifications across database, laboratory, reporting, patient portal, and inpatient systems.

Projects

Marian: Interactive stock data visualization

Angular TypeScript CSS

Pause: Interactive long-term planning tool

React JavaScript Python Flask

Thought Writer: Social journaling application

JavaScript Python Flask PostgreSQL AWS

CanvaShare: Collaborative drawing gallery

JavaScript Python Flask PostgreSQL AWS

Education

Cornell University

Bachelor of Arts in Biology and Psychology
-

Double major in Biology, with a concentration in Neurobiology & Behavior, and Psychology; minors in Biomedical Engineering and Global Health.

Interests

Technology

  • Applied AI
  • Data visualization
  • Device integration
  • Product design

Research

  • Neuroscience
  • Behavioral science
  • Healthcare
  • Dream science

Outside Work

  • Photography
  • Travel
  • Hiking
  • Cycling